We age because our cells begin to break down as we get older. Is it possible to rejuvenate the skin by stimulating these cells via cutting edge mesenchymal derived stem cells and sending special signals to regrow these cells?
Let’s discuss. Aging is a natural process that occurs as a result of many factors, including:
- Cellular breakdown: Cells break down naturally over time.
- Damage accumulation: Damage to cells, tissues, and genetic material accumulates and cannot be repaired by the body.
- Telomere shortening: The ends of chromosomes, called telomeres, shorten with each cell replication, eventually signaling the cell to stop dividing.
- Senescence: Cells enter a phase called senescence, where they lose their ability to repair themselves and regenerate.
- Environmental factors: Stress, air pollution, tobacco smoke, alcohol consumption, malnutrition, and exposure to ultraviolet radiation (UV) can trigger senescence.
- Genetic factors: Family history can trigger senescence.
What keeps the skin young?
Skin is made up of connective tissue that consists of cellular components and an extracellular matrix (outside cells). The extracellular matrix contains two main types of macromolecules: polysaccharide glycosaminoglycans and collagens. Healthy connective tissue contributes to the appearance of youthful skin by holding it upright while tissues producing collagen support good skin quality.
These skin tissues are also composed of cells called fibroblasts that contribute to collagen deposition and remodeling. The percentage of these cells is 100% until about 28-30 years of age.
When and how does the skin begin to age?
“Skin aging” begins around 28-30 years of age. It is around this time that the connective tissues and fibroblast cells that are responsible for generating collagen begin to break down and die at a rate of 2% annually.
Assuming that this process begins in our 20s, by the time we reach 40, theoretically we lose more than 20% of fibroblast cells in our skin, which means that we lose more than 20% of connective tissues. As mentioned, healthy connective tissue is responsible for keeping the appearance of uplifted skin. As for the collagen that contributes to good skin quality , the more collagen the more youthful the skin appears.
Therefore, with this steady decrease the appearance of fine lines, skin sagging, jowls and other signs of aging begin to appear.
Fibroblast cells are cross-linked to each other, almost like that of mesh. When there are less of these cells as the years pass by, the mesh begins to break; in short, the connective tissue begins to descend. The collagen-producing tissues also deform and our skin easily wrinkles and becomes demarcated. As such, it begins to assume an older appearance. As this cycle repeats and cell death continues as our age progresses, our skin increasingly looks older with time.
Is it possible to restore and sustain young skin with stem cell therapy?
It is possible to replenish fibroblast cells that decrease in number with aging. We can restore and maintain a youthful appearance by regenerating fibroblast cells through stem cell therapies. Mesenchymal derived stem cells found within umbilical birth tissue are the latest in anti aging medicine. The role of stem cells is to act as the progenitor cells ie parent cells that continue to reproduce and grow new healthy cells. Rich in exosomes, hyaluronic acid, and glycosaminoglycans these birth tissue byproducts may offer the anti aging and restorative properties necessary for the cell to cell signaling required for tissue regeneration and healing.
How is skin rejuvenation with stem cell facial treatment performed?
Various methods exist for the ultimate skin rejuvenation including stem cell injections for face. At E&G Aesthetic Institute we combine various techniques to incorporate the benefits of stem cell therapy with Skinpen Collagen Induction Therapy for maximum results and maximum collagen production. The ethically sourced HCT/Ps rich in exosomes, Wharton’s jelly derived mesenchymal stem cells mscs, hyaluronic acid, glycosaminoglycans and birth tissue byproducts in conjunction with our biostimulators and collagen induction therapies produce maximum results.
To which regions can stem cell therapy be applied?
- Face and Facial Skin: Stem cell facial rejuvenation softens wrinkles and fine lines, skin laxity due to decreased collagen and elastin fibers associated with aging as well as sun spots and acne scars.
- Neck, Jowl and Cleavage: It treats wrinkles, sagging, jowling, and hyperpigmented areas and sun spots via paracrine signaling mechanisms that address aging related loss of skin and subcutaneous tissue.
- Hand: It removes a gaunt appearance and minimizes age spots which result from decreased subcutaneous tissue and increased skin laxity over time.
- Joints: The cells regrow healthy tissue to allow your joints to heal. Patients have reported that osteoarthritis, tendonitis, and muscle and soft tissue pain are mitigated 3-6 months following direct administration to the area.
Who can have stem cell skin therapy and what are stem cell side effects ?
While there are a variety of factors to consider with each individual patient, the main contraindication to stem cell therapy including stem cells for face is having a history of an organ transplant. On the other hand, anyone with unwanted wrinkles, laxity, sagging, spots, scars on their skin may benefit from this treatment. It has no age limit and while side effects are rare, it is important that you thoroughly discuss your medical history with your provider.
What are the benefits of stem cell skin therapy?
The most important aspect of stem cell treatment applied to the skin is to restore what is missing, repair and regenerate the tissue. When we are young, we have an adequate number of fibroblast and collagen producing cells in our body. Over time, the number of cells decreases regionally.
Other benefits of a stem cell facial and stem cell therapy for skin and soft tissues include:
- Modulating the immune system Stem cells can help reduce abnormal immune responses
- Reducing inflammation Stem cells can secrete anti-inflammatory factors, which can help alleviate symptoms of chronic inflammatory conditions
- Improving quality of life Stem cell therapy can address the root causes of degenerative diseases and injuries, which can enhance the overall quality of life for patients in the long term
Can I resume daily activities immediately after having stem cell skin therapy?
Immediately after the application there are a few activities to avoid. Anticipate redness of the area and a “sunburn” like sensation for a period of 48 – 72 hours post treatment. During this period avoid strenuous exercise that can lead to excessive perspiration, heated environments like saunas and steam rooms, and avoid picking the area as it may peel or feel like “sand-paper” during the first week. Avoid use of any facial washes and facial products with active ingredients such as AHAs, retinol, vitamin C or other for the first 7 days post treatment. Wear spf +50 or above daily beginning 24 hours after treatment for a period of at least 3 weeks. Your licensed medical provider at E&G Aesthetic Institute will discuss your full aftercare instructions at your stem cell facial appointment.
When do the effects of stem cell skin therapy become visible?
The skin’s self-repair process takes place slowly so the maximum effect is achieved 3-6 months later. Facial stem cell injections or stem cell for face rejuvenation topical application results in some patients may take up to 4 to 6 months.
Is facial stem cell treatment used for rejuvenation therapies only?
Stem cell therapy for face is a method used not only for facial rejuvenation but also for the treatment of cutaneous and subcutaneous skin problems such as acne-scar pit reduction, sunspots, minimizing of large pores, healing of cuts and scars, improvement of sagging skin, etc. Other applications of stem cell therapy include regeneration of joints secondary to osteoarthritis or degenerative joint disease, especially of the knee, shoulder, wrist and lateral hips. Other applications include hair restoration Newport Beach and hair transplant preservation.
How are deep acne scars and surgery scars treated?
Deep acne scars, rolling scars and surgery scars can be treated with combination therapy utilizing subcision techniques to release the tethering of internal scar tissue contributing to a rough textured appearance, utilization of proper depth of SkinPen microneedling therapy and application of topical and subcutaneous administration of stem cell therapy and stem cell treatment for face. Your specific treatment and will be tailored to you and your skin concerns.
Frequently Asked Questions
What is the difference between facial fat injections and stem cell therapy?
Facial fat transfer injections utilize a person’s own fat to replace lost volume. This is often described as a more permanent filler as it is obtained when the fat removed via liposuction from a person is reinjected in areas of volume loss such as the cheeks or midface. This is different than stem cell therapy as stem cell therapy harnesses the regenerative power of stem cells to regenerate tissue, which are extracted from sources like fat, bone marrow, or umbilical derived birth tissue and injected to promote healing and repair damaged tissue, potentially leading to longer-lasting results compared to a standard fat injection alone; essentially, stem cell therapy harnesses the regenerative potential of the cells not just the fat itself.
Is there an age limit for stem cell treatment applied to the face or stem cells for wrinkles?
No, there is no age limit for a stem cell facial or stem cell therapy.
How long does the effect of stem cell treatment applied to the face last?
With stem cell therapy, the results continue to improve over time. We generally recommend 3-6 sessions with traditional SkinPen microneedling but when coupled with stem cell therapy, you may reap the benefits in as little as 1 – 3 sessions spaced 4-6 weeks apart. The effects are most notable 3-6 months after treatment.
What are the differences between stem cell for skin regeneration applied to the face and a filling procedure?
Depleted cells are restored with stem cell therapy and rejuvenation with a structure matching the original is ensured. Therefore, the effect of stem cell treatment is a good option compared to non-permanent filling procedure. When the goal is volume loss restoration, dermal fillers for the cheeks and dermal fillers for undereyes at E&G Aeshetic Institute may be a better option.
Is it possible to apply stem cell therapy to lips?
Stem cell therapy can be applied to the lip region as well as to all parts of the face. As years go by, signs of aging begin to appear in the lips in the form of perioral lines ie “smoker’s lines”. As lips become thinner and lines and wrinkles begin to form around them, stem cell therapy helps reduce wrinkles, refining fine lines and softening perioral wrinkles.
How much does stem cell skin treatment cost?
The cost of a stem cell facial or stem cell skin treatment in Orange County depends on the quality of the stem cells, number of stem cells, the types of stem cells , and the quality of the placental derived birth tissue. There are various options to choose from with some options having a higher concentration of mesenchymal derived stem cells, exosomes, glycosaminoglycans, hyaluronic acid and other special proteins to choose from.
What is Wharton’s Jelly?
Wharton’s jelly is a soft, gelatinous substance that surrounds and protects the umbilical cord in a developing fetus. It is composed of:
- Mesenchymal stem cells mscs: These cells have the potential to develop into various types of tissues, such as bone, cartilage, and fat.
- Extracellular matrix: These cells include proteins like collagen and hyaluronic acid, which provide skin structure and support to the jelly.
- Blood vessels: These carry nutrients and oxygen to the fetus.
Wharton’s jelly plays a crucial role in fetal development by:
- Protecting the umbilical cord: It cushions and insulates the blood vessels from injury.
- Facilitating nutrient and waste exchange: The stem cells and extracellular matrix help regulate the flow of oxygen, nutrients, and waste products between the fetus and placenta.
- Providing a source of stem cells: Mesenchymal stem cells mscs from Wharton’s jelly can be harvested and used in regenerative medicine to treat various conditions, such as osteoarthritis and heart disease.
What is the difference between PRP and Stem Cell Therapy for Face?
PRP (Platelet-Rich Plasma) and Stem Cell Therapy are regenerative treatments with distinct mechanisms. PRP, derived from the patient’s blood, uses platelets rich in growth factors to stimulate healing and tissue repair, commonly used for mild skin rejuvenation, fine lines, reducing wrinkles, and hair growth. In contrast, Stem Cell Therapy utilizes undifferentiated cells from sources like bone marrow, fat or umbilical derived birth tissue (Wharton’s Jelly) to regenerate damaged tissues, offering more potent healing for severe conditions or deeper tissue repair. While PRP is cost-effective and best for mild to moderate concerns, stem cells provide advanced regeneration for more significant damage. Both treatments can be combined for enhanced results in aesthetics and medicine. Stem cell injections for skin and stem cell injection cosmetic are often a topic of discussion.